My scientific publications in books and peer reviewed journals:


Analysis of the airflow features and ventilation efficiency of an Ultra-Clean-Air operating theatre by qDNS simulations and experimental validation.


Carlos A. Duque-Daza; Jairo Murillo-Rincón; Andrés S. Espinosa-Moreno; Federico Alberini; Alessio Alexiadis; Diego A. Garzón-Alvarado; Andrew M.C. Thomas; 

Mark J.H. Simmons

Building and Environment

DOI: 10.1016/j.buildenv.2024.111444


LAT1 enables T cell activation under inflammatory conditions.

Ogbechi J, Wright HL, et al.

J Autoimmun. 2023 Jul;138:103031.  doi: 10.1016/j.jaut.2023.103031.  Epub May 23.


Letter to the Editor: Postoperative Infection After Total Hip Replacement With Special Reference to Air Contamination in the Operating Room.

Thomas AM, Wilkinson MA. 

Clin Orthop Relat Res. 2023 May 1;481(5):1053-1054.  

doi: 10.1097/CORR.0000000000002589. Epub 2023 Feb 16.


Changes in orthopaedic operating theatre practice, monitored using settle plates.

Thomas AM, Wilkinson MA, Garvey MI.

Ann R Coll Surg Engl. 2022 Sep;104(8):600-604.  doi: 10.1308/rcsann.2021.0328.


Updated Briefing & Guidance on Considerations for the Ventilation Aspects of Healthcare Facilities for Coronavirus

Poplett A et al. (Clinical advisor)

Specialised Ventilation for Healthcare Society Document SVHSoc.03-V4.


Use of Disposable Perioperative Jackets and Surgical Site Infections.

Thomas AM.

JAMA Surg. 2020 Mar 4. doi: 10.1001/jamasurg.2019.6371


The effectiveness of ultra-clean air operating theatres in the prevention of deep infection in joint arthroplasty surgery.

Thomas AM, Simmons MJ.

Bone Joint J. 2018 Oct;100-B(10):1264-1269. 


Effect of an exfoliating skincare regimen on the numbers of epithelial squames on the skin of operating theatre staff, studied by surface microscopy.

Wernham AG, Cain OL, Thomas AM.

J Hosp Infect. 2018 Oct;100(2):190-194.


Aspirin and the prevention of venous thromboembolism following total joint arthroplasty: commonly asked questions.

Azboy I, Barrack R, Thomas AM, Haddad FS, Parvizi J.

Bone Joint J. 2017 Nov;99-B(11):1420-1430.


Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts.

Crowley T, O'Neil JD, Adams H, Thomas AM, Filer A, Buckley CD, Clark AR.

Arthritis Res Ther. 2017 Feb 10;19(1):35


Oxford scores as a triage tool for lower limb arthroplasty lead to discrimination and health inequalities

Robb CA, McBryde CW, Caddy SJ, Thomas AM, Pynsent PB.

Annals of the Royal College of Surgeons of England Supp 2013; 95: 1-4 


Choice Framework for local Policy and Procedures 01-01 –

Management and decontamination of surgical instruments (medical devices) used in acute care.

Andrew Thomas (Co-author on behalf of the Royal College of Surgeons of England)

DOH publications 2012


Hip abductor re-attachment audited using a wire marker.

Gulraj M, Thomas AM, Pynsent PB.

Acta Orthopaedica Belgica. 77-4, 494-496, 2011.


The response of T cells to interleukin-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue.

Hidalgo E, Essex SJ, Yeo L, Curnow SJ, Filer A, Cooper MS,

Thomas AM, McGettrick HM, Salmon M, Buckley CD, Raza K,

Scheel-Toellner D.

Arthritis Rheum. 2011 Nov;63(11):3284-93


The influence of head size and sex on the outcome of Birmingham hip resurfacing.

McBryde CW, Theivendran K, Thomas AM, Treacy RB, Pynsent PB.

J Bone Joint Surg Am. 2010 Jan;92(1):105-12


Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss.

Kaur K, Hardy R, Ahasan MM, Eijken M, van Leeuwen JP, Filer A, Thomas AM, Raza K, Buckley CD, Stewart PM, Rabbitt EH,

Hewison M, Cooper MS.

Ann Rheum Dis. 2010;  69(6):1185-90. 


Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways.

Filer A, Bik M, Parsonage GN, Fitton J, Trebilcock E, Howlett K, Cook M, Raza K, Simmons DL, Thomas AM, Salmon M, Scheel-Toellner D, Lord JM, Rabinovich GA, Buckley CD.

Arthritis Rheum. 2009 Jun;60(6):1604-14. 


Intertrochanteric fracture below Birmingham Hip Resurfacing: 

Successful non-operative management in two cases.

Morgan D, Myers, G, O’Dwyer K, Thomas AM.

Injury Extra 2008; 39, 313—315


Changes in body weight following lower limb arthroplasty.

Mughal E, Desai P, Ashraf F, Khan Y,  Dunlop D, Treacy RB, and Thomas AM.

J Bone Joint Surg Br Proceedings

Jul 2008; 90-B: 319.


The influence of surgical approach on outcome in Birmingham Hip Resurfacing.

McBryde CJ, Revell MP, Thomas AM, Treacy RB, Pynsent PB.

Clinical Orthopaedics and Related Research. 

Apr;466(4):920-6, 2008.


Chapter in:  Modern Hip Resurfacing

McMinn, Derek J.W. (Ed.) 

Springer  2008, ISBN: 978-1-84800-087-2


Differential Survival of Leukocyte Subsets Mediated by 

Synovial, Bone Marrow, and Skin Fibroblasts

Filer A, Thomas AM, Lord J, Salmon M, Buckley al.

Arthritis and Rheumatism Vol. 54, No. 7, July 2006, pp 2096–2108


Metatarsal head resection in the rheumatoid foot: 5-year follow-up with and without resection of the first metatarsal head.

Hulse N., Thomas AM.

J Foot Ankle Surg. 2006 Mar-Apr;45(2):107-12. 


Anaemia in a patient with rheumatoid arthritis recovering from revision of a hip replacement.

Prabu A, Bhosle J, Duddy MJ, Thomas AM, Rankin EC.

Rheumatology (Oxford). 

2005 Nov;44 (11): 1461


The role of leukocyte-stromal interactions in chronic inflammatory joint disease.

Burman A, Haworth O, Bradfield P, Parsonage G, Filer A, Thomas AM, Amft N,

Salmon M, Buckley CD.

Joint Bone Spine. 

2005 Jan;72(1):10-6. 


Detection of differentially expressed genes in synovial fibroblasts by

restriction fragment differential display.

Scaife S, Brown R, Kellie S, Filer A, Martin S, Thomas AM,

Bradfield PF, Amft N, Salmon M, Buckley CD.

Rheumatology (Oxford). 

2004 Nov;43(11):1346-52.


Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12),  which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue.

Bradfield PF, Amft N, Vernon-Wilson E, Exley AE, Parsonage G, Rainger GE, Nash GB, Thomas AM, Simmons DL, Salmon M, Buckley CD.

Arthritis and Rheumatism

2003 Sep;48(9):2472-82. 


Debridement arthroplasty for osteoarthritis of the elbow.

Pimpalnerkar AL, Sloan R, Thomas AM.

J Bone Joint Surg Br Proceedings, 

Jul 2002; 84-B: 171. 


Measuring Performance in the NHS:  What Really Matters?  

Appleby J, Thomas AMC.

British Medical Journal.

320:1464-1467, 2000.


Growth of Pakistani children in relation to the 1990 growth standards

Kelly AM, Shaw NJ, Thomas AM, Pynsent PB, Baker DJ

Archives of Disease in Childhood 

77: 401-405, 1997.


Multiple Rice Body Formation of Chronic Sub-acromial/Sub-deltoid Bursitis

Griffith JH, Pels WC, Evans NS, Smallman LA, Won RW,

Thomas AM. 

Clinical Radiology 

51: 511-514, 1996.


Chapter: Measurement of Vertebral Bloodflow and its significance in Disc Disease 

In: Lumbar Spine Disorders, Current Concepts

Editors Aspden and Porter.  Publisher  World Scientific 1995.


Surgical Management of Haemangioendothelioma of the Spine.  

Marks DS, Thomas AM, Thompson AG, Mills S.

European Spine Journal 

4: 186-190, 1995.


Chapter: The Spine

In:  Outcome Measures in Orthopaedics

Editors Pynsent, Fairbank and Carr.  Butterworth 1993.


The Effect of Polymethylmethacrylate Bone Cement Vibration on the Bone-Cement Interface.  

Thomas AMC, McMinn DJW, McCall I, Haddaway M.

Cells and Materials

2: 163-168, 1992.


Methods of Testing for Orthopaedic Bone Staples, 

McCombe PF, Thomas AMC, Pynsent PB, Thompson AG.

Journal of the American Society for Testing and Materials.  

April 1992.


The response of the human femur to mechanical vibration

Thomas AMC, Luo DZ, Dunn JW.

Journal of Biomedical Engineering

13: 58-60, 1991.


Pullout force of power-driven staples in cadaveric femoral metaphysis

McCombe PF, Thomas AMC, Pynsent PB, Thompson AG.

Journal of Orthopaedic Trauma

4: 158-162, 1990.


Benign haemangioma of bone in a middle phalanx

Thomas AMC, Mulligan PJ, Jones L.

The Journal of Hand Surgery

15(4): 484-486, 1990.


A computer interview system for patients with back pain 

Thomas AMC, Fairbank JCT, Pynsent PB, Baker D.


14: 844-846, 1989.


The BOA Orthopaedic Growth Record

Thomas AMC.

Ware: Castlemead Publications

November 1989.


Effect of low frequency vibration on the flow of polymethymethacrylate bone cement

Thomas AMC, Dunn JW, Luo DZ.

The Lancet, letters

i: 116-7, 1988.


Retained surgical swab debris in post laminectomy arachnoiditis and peridural fibrosis

Hoyland J, Freemont AJ, Denton J, Thomas AMC, McMillan JJ, Jayson MIV.

The Journal of Bone and Joint Surgery

70B: 659-662, 1988.


The microsurgical treatment of lumbar disc protrusion

Thomas AMC, Afshar F.

The Journal of Bone and Joint Surgery

69-B: 696-698, 1987.


Rest pain and leg ulceration due to syphilitic osteomyelitis of the tibia

Waltzman M, Wade AAH, Drake SM, Thomas AMC.

British Medical Journal

293: 804-805, 1986.


Incompetent perforating vein ligation in the treatment of venous ulceration 

Thomas, AMC, Tomlinson PJ, Boggon, RP.

Annals of the Royal College of Surgeons of England

68: 214-215, 1986.


Venous ulceration in hypogonadal men

Thomas AMC.

The Lancet, letters

ii: 1103,1982.


Simultaneous presentation of two cerebral arterial aneurysms

Thomas AMC.

Postgraduate Medical Journal

60: 135-136, 1984.


Bromocriptine induced cerebrospinal fluid rhinorrhoea

Afshar F, Thomas AMC.

Surgical Neurology

18: 61-63, 1983.



Some great people from the history of Orthopaedics:

The anatomical studies of Leonardo da Vinci, from around 1510, are one of the great achievements of the Italian renaissance.  His work helped to lay the foundations of modern scientific medicine, and orthopaedics in particular


Pioneering Orthopaedic Surgeon Professor Sir John Charnley using the lathe in his workshop at home. John Charnley radically changed the treatment of hip arthritis with his total hip replacement designed in the early 1960s. 


Mr Mike Freeman of The London Hospital sitting with Dr John Insall  (right) of The Hospital for Special Surgery, New York in Mike Freeman's garden in about 1980.  These two individuals were responsible for working out questions of design, balance and alignment which are the basis of all good modern Total Knee Replacements.